@article{Ovonramwen_2021, title={Synthesis of 1-(2,4-Dinitrophenyl)-3,5-diphenyl-1H-pyrazol-4-ol via trans-1,3-Diphenyl-2,3-epoxy-1-propanone}, volume={47}, url={https://tjs.udsm.ac.tz/index.php/tjs/article/view/785}, DOI={10.4314/tjs.v47i3.32}, abstractNote={<p>The <em>trans-</em>1<em>,</em>3-diphenyl-2,3-epoxy-1-propanone was synthesized from benzaldehyde and 2-bromoacetophenone in 20 min which is more economical. The presence of ethanol and Br in 2-bromoacetophenone facilitated the reaction. The vicinal diaxial coupling constant of <em>trans-</em>1<em>,</em>3-diphenyl-2,3-epoxy-1-propanone was zero, an indication of <em>trans</em> configuration for a rigid 3-membered ring at ~90<sup>o</sup> dihedral angle. 1-(2,4-Dinitrophenyl)-3,5-diphenyl-1<em>H</em>-pyrazol-4-ol was synthesized from <em>trans</em>-1,3-diphenyl-2,3-epoxy-1-propanone and 2,4-dinitro phenylhydrazine in glacial CH<sub>3</sub>COOH to give 85.5% yield and characterized using FTIR, <sup>1</sup>H, <sup>13</sup>C NMR, DEPT 135 and MS spectra. The 1-(2,4-dinitrophenyl)-3,5-diphenyl-1<em>H</em>-pyrazol-4-ol can be exploited for unique biological activities and in the synthesis of synthetic fibers.</p> <p><strong>Keywords:    </strong>1-(2,4-dinitrophenyl)-3,5-diphenyl-1<em>H</em>-pyrazol-4-ol, <em>trans</em>-1,3-diphenyl-2,3-epoxy-1-propanone, synthesis, 2,4-dinitro phenylhydrazine.</p>}, number={3}, journal={Tanzania Journal of Science}, author={Ovonramwen, Oluwaseyi B}, year={2021}, month={Aug.}, pages={1243–1251} }